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The Weight-Loss Drugs Are Changing. Your Body's Rules Are Not.

Nutrition  ·  Nov 1, 2026  ·  6 min read

In October, the EU's medicines agency recommended approval of a daily weight-loss pill. A few days ago, a new injection was reported to give more than twice the weight loss of Ozempic in people with type 2 diabetes. It has never been easier to imagine a future where weight is something you simply medicate away.

Then there is the number that rarely makes the headlines. One year after stopping treatment, people have on average regained about 60 percent of the weight they lost.

I lost 34 kilos through food, daily movement and training, and the weight has stayed off. I am not against these medicines. For many people with obesity they are a real medical treatment. But no medicine changes what your body needs to keep its muscle, and that is the part you can start on today.

What is new right now

Why the weight comes back

A review of 48 studies, published in eClinicalMedicine in 2026, found that about 60 percent of the lost weight was back after a year. The researchers estimate that the regain levels off at about 75 percent.

That is not a lack of character. These drugs turn down hunger for as long as you take them, and when you stop, the effect wears off. If your habits have not changed while you were on the medicine, the old conditions are waiting for you. So the months on treatment are also the best time to build new habits, while eating less feels easier.

Protein: the weight you want to keep

The scales do not tell you what you have lost. In a large study of semaglutide, people lost an average of 13.6 kilos in the part of the study that measured body composition. Of that, 5.3 kilos, or 38 percent, was lean mass. Lean mass is not only muscle, and a joint advisory from four American medical societies estimates that about 20 percent of the total weight loss was muscle.

Muscle keeps you strong, helps you get up the stairs and matters more and more with age. And when the appetite shrinks, protein tends to shrink with everything else.

The same advisory mentions 1.2 to 1.6 grams of protein per kilo of body weight a day as a higher target while losing weight. For someone who weighs 80 kilos, that is about 95 to 130 grams. At a high body weight, the calculation is often based on an adjusted weight instead, and the calculator below does that for you.

You can read more in our articles on protein and eating after 65. If you have kidney disease, follow the advice from your doctor or dietitian.

Daily movement: the unglamorous winner

A review of 14 trials and 3,758 adults, published in 2026, looked at walking in weight-loss programs. The participants went from about 7,300 steps a day to about 8,500, and were still at about 8,200 in the maintenance phase. More steps did not explain how much weight people lost while dieting. But those who raised their step count and kept it up regained less. The result is an association and not proof, but it fits with what many of us notice in everyday life.

A Danish trial with 109 adults points the same way. In the year after treatment ended, those who had taken the drug liraglutide alone regained 6.0 kilos, compared with 2.5 kilos for those who had combined it with supervised exercise. It is one small trial of an older drug, so it should not be stretched too far.

For me, it began with walks with our huskies, 40 or 50 minutes in the morning air. It was not much of a workout at first. But it happened every day, and that is what matters. If you want to get more out of your walks, try Japanese walking.

Calculate your own balance

Whether or not you take a medicine, the balance between what you eat and what you burn still matters. Change the example values to your own, and everything is calculated as you type. Nothing you enter is saved or sent anywhere.

The result is an estimate, and it can easily be off by a few hundred kilocalories. Use it to compare, for example what 2,000 more steps or a smaller snack would change. Your weight over a few weeks tells you more than any calculator, and the weekly figure gets less accurate over time as your body adapts. The calculator is not meant for children or for use during pregnancy. If you have or have had an eating disorder, please skip it and talk to your care provider instead.

If you are thinking about medication

What is still yours

The medicines will keep getting better, and that is good news for many people. But a medicine cannot go for a walk for you, lift a weight for you or put protein on your plate. Whichever way you choose, those habits are what you get to keep.

Start small. Take a walk today, put the protein first at your next meal, and see what your numbers say.